Gang Zheng

Professor (Status-only)

Gang Zheng, BSc (Hangzhou University), PhD (State University of New York at Buffalo), is Professor at the Department of Medical Biophysics (primary), the Leslie Dan Faculty of Pharmacy (cross), the Institute of Biomaterials and Biomedical Engineering (cross), University of Toronto. He is a Senior Scientist and the Joey and Toby Tanenbaum/Brazilian Ball Chair in Prostate Cancer Research at the Princess Margaret Cancer Center, and the Scientific Lead of Nanotechnology and Radiochemistry at the Techna Institute, UHN. He is also an Adjunct Professor of Radiology at the University of Pennsylvania. His primary research interests are nanomedicine, molecular imaging and phototherapy, with focus on clinically translatable technology to combat cancers. His recent porphysome discovery was named one of the “top 10 cancer breakthroughs of 2011” by the Canadian Cancer Society. He is currently leading a CIHR Team Grant on Nanomedicine and also leading the joint UHN/UofT effort in creating a CFI Nanomedicine Fabrication Center.

Prof. Zheng’s lab page

Prof. Zheng’s profile at UHN

Current research topics

  • Nanomedicine
  • Molecular imaging
  • Phototherapy
  • Image-guided intervention
  • Porphyrins

Important Publications

Huynh et al., In Situ Conversion of Porphyrin Microbubbles to Nanoparticles for Multimodality Imaging, Nature Nanotechnology, 2015, 10: 325-332.

Liu et al., Inherently Multimodal Nanoparticle-Driven Tracking and Real-Time Delineation of Orthotopic Prostate Tumors and Micrometastases, ACS Nano 2013, 7: 4221–4232.

Lovell et al., Porphysome Nanovesicles Generated by Porphyrin Bilayers for use as multimodal biophotonic contrast agents, Nature Materials 2011, 10: 324-332.

Zhang et al., Biomimetic Nanocarrier for Direct Cytosolic Drug Delivery, Angewandte Chemie 2009, 48, 9171-9175.

Zheng et al., Photodynamic Molecular Beacon as an Activatable Photosensitizer Based on Protease Controlled Singlet Oxygen Quenching and Activation, Proc Nat Acad Sci  2007, 104:8989-94.

Zheng et al., Rerouting Conjugated Lipoproteins to Selected Alternate Receptor: a Biocompatible Nanoplatform for Delivery of Diverse Diagnostic and Therapeutic Agents, Proc Nat Acad Sci  2005,102:17757-62.

Publications at PubMed for Gang Zheng

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