This research area deals with the development and optimization of drugs, their optimal delivery and maintenance at their sites of action as well as with the molecular diagnostics of human diseases.
The study of physicochemical properties of drugs and interactions with their targets, the development of drug formulations, new materials and strategies for design and controlled delivery of drugs to enhance therapeutic activity, targeted radiotherapeutic agents and molecular imaging agents, are examples of areas under investigation. Activities also include the study of drug transport mechanisms across biological barriers as well as the study of their absorption, distribution, metabolism and elimination, which are important determinants of their biologic activity. The development of new nanomaterials, synthetic biology approaches for disease diagnostic applications, biological therapeutics including viral vector-mediated gene therapy, and the delivery of precision medicine are emerging topics of interest.
Investigators
Research News
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Canadian Hub for Health Intelligence and Innovation in Infectious Diseases awarded $72 million
Biomanufacturing Hub Network (BioHubNet), a CBRF-funded program led by University Professor and Scientific Director of PRiME Molly Shoichet, will address the severe shortage of talents in the biomanufacturing sector.
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Team Rx Participate wins 2024 Business Plan Competition
PharmD students Saphia Mourad, Cynthia Nohra, Lama Alomrani, and Maneli Jafar-Pisheh, collectively known as Team Rx Participate, won the top prize at the annual Business Plan Competition finale.
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U of T researchers target neurogenesis in new approach to treat Parkinson’s disease
Researchers at the Temerty Faculty of Medicine found a way to better control the preclinical generation of key neurons depleted in Parkinson’s disease.
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