
This research area deals with the development and optimization of drugs, their optimal delivery and maintenance at their sites of action as well as with the molecular diagnostics of human diseases.
The study of physicochemical properties of drugs and interactions with their targets, the development of drug formulations, new materials and strategies for design and controlled delivery of drugs to enhance therapeutic activity, targeted radiotherapeutic agents and molecular imaging agents, are examples of areas under investigation. Activities also include the study of drug transport mechanisms across biological barriers as well as the study of their absorption, distribution, metabolism and elimination, which are important determinants of their biologic activity. The development of new nanomaterials, synthetic biology approaches for disease diagnostic applications, biological therapeutics including viral vector-mediated gene therapy, and the delivery of precision medicine are emerging topics of interest.
Investigators
Research News
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PharmD student receives Volunteer Award from Life Sciences Ontario
Simonne Rauch is recognized for her contributions to ambassador and mentorship programs.
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Celebrating Excellence: Mike Folinas Receives 2024-25 Exemplary U of T Ambassador Award
Mike Folinas has received the 2024–25 Exemplary U of T Ambassador Award for his outstanding service and leadership in supporting the academic community.
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Structural biology research takes aim at rare neurodegenerative disease
Rachel Harding leads research to understand protein responsible for Huntington’s disease and advance drug discovery
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