
In this area our teams are elucidating the biochemical and cellular basis of human diseases and the molecular mechanisms underlying drug action and their targets.
Our investigation of disease mechanisms provides insights into identification of novel therapeutic targets for which small molecules or biologics are being developed. Research is directed towards the molecular and cellular mechanisms underlying the function of therapeutic targets, correcting the target using gene therapy, and the intracellular signalling pathways they control and the mechanistic study of drug action. Approaches incorporate human studies, patient-derived samples and animal models of disease. Our research teams are interested in several human diseases or conditions including drug addiction, autism, diabetes, cancer, genetic disorders, infectious diseases, and neurological diseases.
Investigators
Research News
Image

Grad to Watch: Jackie Fule Liu’s research focuses on better outcomes for diabetes patients
A recent PhD graduate, Jackie Fule Liu combines hands-on skill and big-picture thinking to help tackle diabetes care challenges.
Read More
Image

U of T community members recognized with Order of Canada
Congratulations to Dean Emeritus and Professor K. Wayne Hindmarsh on his appointment.
Read More
Image

Welcoming Ivy Lam as Academic Lead in Climate, Health & Sustainable Care
Assistant Professor Lam will guide the Leslie Dan Faculty of Pharmacy's efforts to embed environmental sustainability across the Faculty.
Read More