![Drug Discover and Disease Diagnostics Banner Stored microchips used for disease diagnostics](/sites/default/files/styles/scale_width_1250/public/images/2019-11/drug_discovery_and_disease_diagnostics.jpg?itok=t3l2jjBZ)
This research area deals with the development and optimization of drugs, their optimal delivery and maintenance at their sites of action as well as with the molecular diagnostics of human diseases.
The study of physicochemical properties of drugs and interactions with their targets, the development of drug formulations, new materials and strategies for design and controlled delivery of drugs to enhance therapeutic activity, targeted radiotherapeutic agents and molecular imaging agents, are examples of areas under investigation. Activities also include the study of drug transport mechanisms across biological barriers as well as the study of their absorption, distribution, metabolism and elimination, which are important determinants of their biologic activity. The development of new nanomaterials, synthetic biology approaches for disease diagnostic applications, biological therapeutics including viral vector-mediated gene therapy, and the delivery of precision medicine are emerging topics of interest.
Investigators
Research News
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![Celene Titus, PhD candidate Celene Titus, PhD candidate](/sites/default/files/styles/landscape_4_3_600/public/images/2024-07/celene_titus_featured.jpg?itok=5zflGERW)
Faces of PharmSci: Celene Titus
PhD student Celene Titus is working in the field of HIV-Associated Neurocognitive Impairments (NCI) and brain inflammation to improve HIV patients' quality of life and deepen our understanding of brain inflammation in HIV infection.
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![Darius Rackus, Molly Shoichet, and Gilbert Walker Darius Rackus, Molly Shoichet, and Gilbert Walker](/sites/default/files/styles/landscape_4_3_600/public/images/2024-07/biohubnet_featured.jpg?itok=TL8QwP6W)
BioHubNet set to bridge academia and industry to strengthen Canada’s biomanufacturing talent pipeline
To kick-off the new launched Biomanufacturing Hub Network (BioHubNet) initiative, partners and collaborators met at U of T's Hart House to address key challenges in Canada's biomanufacturing sector.
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![Graduate Research in Progress (2024) Committee Graduate Research in Progress (2024) Committee](/sites/default/files/styles/landscape_4_3_600/public/images/2024-06/grip_2024_featured.jpg?itok=UZygswBz)
Exploring Tomorrow's Breakthroughs: GRIP 2024
Last week, the Leslie Dan Faculty of Pharmacy hosted its 2024 GRIP symposium, attended by 200 faculty, staff, and students, showcasing diverse graduate student research.
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