This research area deals with the development and optimization of drugs, their optimal delivery and maintenance at their sites of action as well as with the molecular diagnostics of human diseases.
The study of physicochemical properties of drugs and interactions with their targets, the development of drug formulations, new materials and strategies for design and controlled delivery of drugs to enhance therapeutic activity, targeted radiotherapeutic agents and molecular imaging agents, are examples of areas under investigation. Activities also include the study of drug transport mechanisms across biological barriers as well as the study of their absorption, distribution, metabolism and elimination, which are important determinants of their biologic activity. The development of new nanomaterials, synthetic biology approaches for disease diagnostic applications, biological therapeutics including viral vector-mediated gene therapy, and the delivery of precision medicine are emerging topics of interest.
Investigators
Research News
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What can professional regulators do about society’s biggest problems?
Professor Zubin Austin explores role of regulators in tackling challenging issues, such as climate change.
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Faces of PharmSci: Luis Armando Pérez Dávalos
PhD student Luis Armando Pérez Dávalos is developing organ-on-a-chip models, aiming to evaluate nanomedicine-based therapies for maternal-fetal diseases.
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U of T Pharmacy alumni fill critical gaps in patient care
Ajay Chahal and Anushya Vijayaraghevan innovate pharmacy practice to improve patient access to medication.
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